Profile Photo

Paul Friedrich

PhD Student

Center for medical Image Analysis & Navigation (CIAN)

University of Basel

About Me

I am a third year PhD student at the Center for medical Image Analysis and Navigation (CIAN) of the University of Basel. My work is supervised by Philippe Cattin and Florian Thieringer.

I'm interested in medical image analysis, implicit neural representations, 3D deep learning and generative modeling. My current research is part of the MIRACLE II project and focuses on conditional shape generation and manipulation tasks as well as (un)conditional 3D medical image generation. I'm particularly interested in different types of 3D data representations, including voxel grids, point clouds, meshes, triplanes, and neural implicit representations.

News & Updates

March, 2025

Journal Paper Published

Our paper Generating 3D Pseudo-Healthy Knee MR Images to Support Trochleoplasty Planning which has previously been early-accepted to IPCAI has been published in the International Journal of Computer Assisted Radiology and Surgery.

February, 2025

New Preprint

Our paper MedFuncta: Modality-Agnostic Representations Based on Efficient Neural Fields is available on arXiv. We introduce a modality agnostic continuous data representation based on meta-learned neural fields (NFs) and show how NFs can be generalized from single instances to large datasets. We further demonstrate that we can solve relevant downstream tasks by applying nerual networks to this permutation-equivariant functional representation.

December, 2024

Book Chapter Published

Our review chapter Deep Generative Models for 3D Medical Image Synthesis has been published in Generative Machine Learning Models in Medical Image Computing. We review deep generative models (VAEs, GANs, and DDMs) for 3D medical image synthesis, covering basic principles, advances, and application for relevant downstream tasks. The chapter also addresses evaluation metrics for image fidelity, diversity, utility, and privacy.

Publications

A collection of my published research articles. First-author contributions are highlighted.

MedFuncta: Modality-Agnostic Representations Based on Efficient Neural Fields
Paul Friedrich, Florentin Bieder, Philippe C. Cattin
arXiv preprint, 2025
@article{friedrich2025medfuncta, title={MedFuncta: Modality-Agnostic Representations Based on Efficient Neural Fields}, author={Friedrich, Paul and Bieder, Florentin and Cattin, Philippe C}, journal={arXiv preprint arXiv:2502.14401}, year={2025}}
Generating 3D Pseudo-Healthy Knee-MR Images to Support Trochleoplasty Planning
Michael Wehrli, Alicia Durrer, Paul Friedrich, Volodimir Buchakchiyskiy, Marcus Mumme, Edwin Li, Gyozo Lehoczky, Carol C. Hasler, Philippe C. Cattin
IPCAI (Early Accepted) | International Journal of Computer Assisted Radiology and Surgery, 2025
@article{wehrli2025generating, title={Generating 3D pseudo-healthy knee MR images to support trochleoplasty planning}, author={Wehrli, Michael and Durrer, Alicia and Friedrich, Paul and Buchakchiyskiy, Volodimir and Mumme, Marcus and Li, Edwin and Lehoczky, Gyozo and Hasler, Carol C and Cattin, Philippe C}, journal={International Journal of Computer Assisted Radiology and Surgery}, pages={1--8}, year={2025}, publisher={Springer}}
Deep Generative Models for 3D Medical Image Synthesis
Paul Friedrich, Yannik Frisch, Philippe C. Cattin
Generative Machine Learning Models in Medical Image Computing, 2024
@incollection{friedrich2024deep, title={Deep generative models for 3d medical image synthesis}, author={Friedrich, Paul and Frisch, Yannik and Cattin, Philippe C}, booktitle={Generative Machine Learning Models in Medical Image Computing}, pages={255--278}, year={2024}, publisher={Springer}}
cWDM: Conditional Wavelet Diffusion Models for Cross-Modality 3D Medical Image Synthesis
Paul Friedrich, Alicia Durrer, Julia Wolleb, Philippe C. Cattin
arXiv preprint, 2024
@article{friedrich2024cwdm, title={cWDM: Conditional Wavelet Diffusion Models for Cross-Modality 3D Medical Image Synthesis}, author={Friedrich, Paul and Durrer, Alicia and Wolleb, Julia and Cattin, Philippe C}, journal={arXiv preprint arXiv:2411.17203}, year={2024}}
Binary Noise for Binary Tasks: Masked Bernoulli Diffusion for Unsupervised Anomaly Detection
Julia Wolleb, Florentin Bieder, Paul Friedrich, Peter Zhang, Alicia Durrer, Philippe C. Cattin
International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), 2024
@inproceedings{wolleb2024binary, title={Binary noise for binary tasks: Masked bernoulli diffusion for unsupervised anomaly detection}, author={Wolleb, Julia and Bieder, Florentin and Friedrich, Paul and Zhang, Peter and Durrer, Alicia and Cattin, Philippe C}, booktitle={International Conference on Medical Image Computing and Computer-Assisted Intervention}, pages={135--145}, year={2024}, organization={Springer}}
WDM: 3D Wavelet Diffusion Models for High-Resolution Medical Image Synthesis
Paul Friedrich, Julia Wolleb, Florentin Bieder, Alicia Durrer, Philippe C. Cattin
MICCAI Workshop on Deep Generative Models (DGM4MICCAI), 2024
@inproceedings{friedrich2024wdm, title={Wdm: 3d wavelet diffusion models for high-resolution medical image synthesis}, author={Friedrich, Paul and Wolleb, Julia and Bieder, Florentin and Durrer, Alicia and Cattin, Philippe C}, booktitle={MICCAI Workshop on Deep Generative Models}, pages={11--21}, year={2024}, organization={Springer}}
Modeling the Neonatal Brain Development Using Implicit Neural Representations
Florentin Bieder, Paul Friedrich, Hélène Corbaz, Alicia Durrer, Julia Wolleb, Philippe C. Cattin
International Workshop on PRedictive Intelligence In MEdicine (PRIME @ MICCAI), 2024
@inproceedings{bieder2024modeling, title={Modeling the Neonatal Brain Development Using Implicit Neural Representations}, author={Bieder, Florentin and Friedrich, Paul and Corbaz, H{\'e}l{\`e}ne and Durrer, Alicia and Wolleb, Julia and C. Cattin, Philippe}, booktitle={International Workshop on PRedictive Intelligence In MEdicine}, pages={1--11}, year={2024}, organization={Springer}}
Denoising Diffusion Models for 3D Healthy Brain Tissue Inpainting
Alicia Durrer, Julia Wolleb, Florentin Bieder, Paul Friedrich, Lester Melie-Garcia, Mario Ocampo-Pineda, Cosmin I. Bercea, Ibrahim E. Hamamci, Benedikt Wiestler, Marie Piraud, Özgür Yaldizli, Christina Granziera, Bjoern H. Menze, Philippe C. Cattin, Florian Kofler
MICCAI Workshop on Deep Generative Models (DGM4MICCAI), 2024
@inproceedings{durrer2024denoising, title={Denoising diffusion models for 3D healthy brain tissue inpainting}, author={Durrer, Alicia and Wolleb, Julia and Bieder, Florentin and Friedrich, Paul and Melie-Garcia, Lester and Ocampo Pineda, Mario Alberto and Bercea, Cosmin I and Hamamci, Ibrahim Ethem and Wiestler, Benedikt and Piraud, Marie and others}, booktitle={MICCAI Workshop on Deep Generative Models}, pages={87--97}, year={2024}, organization={Springer}}
MedShapeNet - A Large-Scale Dataset of 3D Medical Shapes for Computer Vision
Jianning Li, Zongwei Zhou, Jiancheng Yang, Antonio Pepe, Christina Gsaxner, Gijs Luijten, Chongyu Qu, Tiezheng Zhang, Xiaoxi Chen, Wenxuan Li, Marek Wodzinski, Paul Friedrich, Kangxian Xie, Yuan Jin, (122 more), Seyed-Ahmad Ahmadi, Ping Luo, Bjoern Menze, Mauricio Reyes, Thomas M. Deserno, Christos Davatzikos, Behrus Puladi, Pascal Fua, Alan L. Yuille, Jens Kleesiek, Jan Egger
Biomedical Engineering / Biomedizinische Technik, 2024
@article{li2025medshapenet, title={Medshapenet--a large-scale dataset of 3d medical shapes for computer vision}, author={Li, Jianning and Zhou, Zongwei and Yang, Jiancheng and Pepe, Antonio and Gsaxner, Christina and Luijten, Gijs and Qu, Chongyu and Zhang, Tiezheng and Chen, Xiaoxi and Li, Wenxuan and others}, journal={Biomedical Engineering/Biomedizinische Technik}, volume={70}, number={1}, pages={71--90}, year={2025}, publisher={de Gruyter}}
Point Cloud Diffusion Models for Automatic Implant Generation
Paul Friedrich, Julia Wolleb, Florentin Bieder, Florian M. Thieringer, Philippe C. Cattin
International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), 2023
@inproceedings{friedrich2023point, title={Point cloud diffusion models for automatic implant generation}, author={Friedrich, Paul and Wolleb, Julia and Bieder, Florentin and Thieringer, Florian M and Cattin, Philippe C}, booktitle={International conference on medical image computing and computer-assisted intervention}, pages={112--122}, year={2023}, organization={Springer}}

GitHub Projects

A collection of my public GitHub repositories.

Invited Talks

2024 – “Diffusion Models for Medical Image Analysis”
Technical University of Munich, Lab for AI in Medicine, Daniel Rückert

Academic Services

Journal Reviewer

  • IEEE Transactions on Medical Imaging (TMI)
  • IEEE Journal of Biomedical and Health Informatics (JBHI)

Conference Reviewer

  • International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI): 2024, 2025
  • Medical Imaging with Deep Learning (MIDL): 2025
  • International Conference on Information Processing in Computer-Assisted Interventions (IPCAI): 2025
  • MICCAI Workshops: 2024, 2025

Others

  • Member of the Integrity Commission @ DBE University of Basel
BibTeX copied to clipboard!