Paul Friedrich

I am a third year PhD student at the Center for medical Image Analysis and Navigation (CIAN) of the University of Basel. My work is supervised by Philippe Cattin and Florian Thieringer. I hold a bachelor's and a master's degree in biomedical engineering, both of which I finished best in class.

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News
  • [10/2024] A preprint of our review book chapter Deep Generative Models for 3D Medical Image Synthesis is available on arXiv.
  • [07/2024] Our paper WDM: 3D Wavelet Diffusion Models for High-Resolution Medical Image Synthesis is accepted at DGM4MICCAI 2024.
  • [07/2024] Our paper Modeling the Neonatal Brain Development Using Implicit Neural Representations is accepted at PRIME@MICCAI 2024.
  • [07/2024] Our paper Denoising Diffusion Models for 3D Healthy Brain Tissue Inpainting is accepted at DGM4MICCAI 2024.
  • [06/2024] Our paper Binary Noise for Binary Tasks: Masked Diffusion Models for Unsupervised Anomaly Detection is accepted at MICCAI 2024.
  • [12/2023] I contributed to the MedShapeNet project - a large large-scale dataset of 3D medical shapes for computer vision.
  • [03/2023] Our paper Point Cloud Diffusion Models for Automatic Implant Generation got accepted at MICCAI 2023.
  • Research

    I'm interested in medical image analysis, computer vision, 3D deep learning and generative models. My current research is part of the MIRACLE II project and focuses on conditional shape generation and manipulation tasks as well as (un)conditional 3D medical image generation. I'm particularly interested in different types of 3D data representations, including voxel grids, point clouds, meshes, triplanes, or neural implicit representations.

    profile photo Deep Generative Models for 3D Medical Image Synthesis
    Paul Friedrich, Yannik Frisch, Philippe C. Cattin
    arXiv preprint, 2024
    arXiv

    A review of deep generative models (VAEs, GANs and DDMs) for 3D medical image synthesis. This book chapter covers fundamental principles, recent advaces, as well as strength and weaknesses of different deep generative models for 3D medical image synthesis and examines their application for relevant downstream tasks. The chapter also reviews commonly used evaluation metrics for assessing image fidelity, diversity, utility and privacy.

    profile photo Modeling the Neonatal Brain Development Using Implicit Neural Representations
    Florentin Bieder, Paul Friedrich, Hélène Corbaz, Alicia Durrer, Julia Wolleb, Philippe C. Cattin
    PRIME@MICCAI, 2024
    Project page / Code / arXiv / Paper

    An implicit neural representation (INR), to predict 2D- and 3D MR images of neonatal brains at varying time points.

    profile photo Denoising Diffusion Models for 3D Healthy Brain Tissue Inpainting
    Alicia Durrer, Julia Wolleb, Florentin Bieder, Paul Friedrich, Lester Melie-Garcia, Mario Ocampo-Pineda, Cosmin I. Bercea, Ibrahim E. Hamamci, Benedikt Wiestler, Marie Piraud, Özgür Yaldizli, Christina Granziera, Bjoern H. Menze, Philippe C. Cattin, Florian Kofler
    DGM4MICCAI, 2024
    Code / arXiv / Paper

    A review on different diffusion models for 3D healthy brain tissue inpainting.

    profile photo Binary Noise for Binary Tasks: Masked Bernoulli Diffusion for Unsupervised Anomaly Detection
    Julia Wolleb, Florentin Bieder, Paul Friedrich, Peter Zhang, Alicia Durrer, Philippe C. Cattin
    MICCAI, 2024
    Code / arXiv / Paper

    A Bernoulli Diffusion Model operating on a binary latent representation of the data to effectively solve an unsupervised anomaly detection task.

    profile photoprofile photo WDM: 3D Wavelet Diffusion Models for High-Resolution Medical Image Synthesis
    Paul Friedrich, Julia Wolleb, Florentin Bieder, Alicia Durrer, Philippe C. Cattin
    DGM4MICCAI, 2024
    Project page / Code / Models / arXiv / Paper / YouTube

    WDM is a framework for high-resolution medical images synthesis. We propose a simple yet effective way of scaling 3D diffusion models to high resolutions (256 x 256 x 256 on a single 40 GB GPU) by applying Discrete Wavelet Transform for spatial dimensionality reduction.

    profile photo MedShapeNet - A Large-Scale Dataset of 3D Medical Shapes for Computer Vision
    Jianning Li, Zongwei Zhou, Jiancheng Yang, Antonio Pepe, Christina Gsaxner, Gijs Luijten, Chongyu Qu, Tiezheng Zhang, Xiaoxi Chen, Wenxuan Li, Marek Wodzinski, Paul Friedrich, Kangxian Xie, Yuan Jin, (122 more), Seyed-Ahmad Ahmadi, Ping Luo, Bjoern Menze, Mauricio Reyes, Thomas M. Deserno, Christos Davatzikos, Behrus Puladi, Pascal Fua, Alan L. Yuille, Jens Kleesiek, Jan Egger
    arXiv preprint, 2023
    Project page / Code / arXiv / Dataset

    MedShapeNet contains over 100,000 medical shapes, including bones, organs, vessels, muscles, etc., as well as surgical instruments. You can search, display them in 3D and download the individual shapes by using our shape search engine.

    profile photo Point Cloud Diffusion Models for Automatic Implant Generation
    Paul Friedrich, Julia Wolleb, Florentin Bieder, Florian M. Thieringer, Philippe C. Cattin
    MICCAI, 2023
    Project page / Code / arXiv / Paper / YouTube

    Following the recent success of diffusion models, we propose a novel approach for automatic implant generation based on a combination of 3D point cloud diffusion models and voxelization networks. Due to the non-deterministic sampling process in our diffusion model, we can propose an ensemble of different implants per defect, from which the physicians can choose the most suitable one.

    Invited Talks
    profile photo Diffusion Models for Medical Image Analysis
    Technical University of Munich, hosted by Daniel Rückert, 2024
    Slides
    Academic Services
    • Conference reviewer: MICCAI, DGM4MICCAI
    • Others: Member of the Integrity Comission @ DBE University of Basel
    Open positions

    I'm currently having an open position for a master's thesis project on Improved Point Cloud Diffusion Models for Automatic Implant Generation. Drop me a mail in case you are interrested.


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